CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation
Abstract. Benzo[ a ]pyrene diol epoxide (BPDE)-DNA adducts are involved in the induction of p53 mutations and probably in the causation of human lung cancer ass
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| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
01 December 2002
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| In: |
Carcinogenesis
Year: 2002, Volume: 23, Issue: 12, Pages: 1969-1977 |
| ISSN: | 1460-2180 |
| DOI: | 10.1093/carcin/23.12.1969 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/carcin/23.12.1969 Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/carcin/article/23/12/1969/2608321 |
| Author Notes: | Kroum Alexandrov, Ingolf Cascorbi, Margarita Rojas, Guy Bouvier, Erik Kriek and Helmut Bartsch |
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