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Reduced poly(ADP‐ribosyl)ation in lymphocytes of laryngeal cancer patients: Results of a case‐control study

Poly(ADP‐ribose) polymerase (PARP), a nuclear enzyme that is catalytically activated by DNA strand breaks, plays a complex role in DNA repair. Using NAD+ as a precursor, it catalyzes the formation of ADP‐ribose polymers, which are attached to various proteins.

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Bibliographic Details
Main Authors: Rajaee-Behbahani, Nahid (Author) , Schmezer, Peter (Author) , Ramroth, Heribert (Author) , Bartsch, Helmut (Author) , Becher, Heiko (Author)
Format: Article (Journal)
Language:English
Published: 12 February 2002
In: International journal of cancer
Year: 2002, Volume: 98, Issue: 5, Pages: 780-784
ISSN:1097-0215
DOI:10.1002/ijc.10234
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/ijc.10234
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/ijc.10234
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Author Notes:Nahid Rajaee‐Behbahani, Peter Schmezer, Heribert Ramroth, Alexander Bürkle, Helmut Bartsch, Andreas Dietz and Heiko Becher
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Summary:Poly(ADP‐ribose) polymerase (PARP), a nuclear enzyme that is catalytically activated by DNA strand breaks, plays a complex role in DNA repair. Using NAD+ as a precursor, it catalyzes the formation of ADP‐ribose polymers, which are attached to various proteins.
Item Description:Gesehen am 12.01.2021
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Physical Description:Online Resource
ISSN:1097-0215
DOI:10.1002/ijc.10234

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