Effects of growth hormone in patients with chronic renal failure: experience in children and adults
Recombinant human growth hormone (GH) has proven effective in promoting growth in short children with chronic renal failure before and after renal transplantation. The action of GH and its mediator insulin-like growth factor 1 on body composition, protein, glucose and bone metabolism offers addition...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2002
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| In: |
Hormone research
Year: 2002, Jahrgang: 58, Pages: 35-38 |
| ISSN: | 1423-0046 |
| DOI: | 10.1159/000066480 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1159/000066480 Verlag, lizenzpflichtig, Volltext: https://www.karger.com/Article/FullText/66480 
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| Verfasserangaben: | Elke Wühl, Franz Schaefer |
| Zusammenfassung: | Recombinant human growth hormone (GH) has proven effective in promoting growth in short children with chronic renal failure before and after renal transplantation. The action of GH and its mediator insulin-like growth factor 1 on body composition, protein, glucose and bone metabolism offers additional therapeutic options. One might be the improvement of the catabolic state in adults with end-stage renal failure. In few pilot studies and two placebo-controlled studies of 6 months duration, GH treatment in adults on dialysis showed clear anabolic effects resulting in a significant increase in lean body mass. |
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| Beschreibung: | Published online: November 17, 2004 Elektronische Reproduktion der Druck-Ausgabe Gesehen am 12.01.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 1423-0046 |
| DOI: | 10.1159/000066480 |