Effects of growth hormone in patients with chronic renal failure: experience in children and adults

Recombinant human growth hormone (GH) has proven effective in promoting growth in short children with chronic renal failure before and after renal transplantation. The action of GH and its mediator insulin-like growth factor 1 on body composition, protein, glucose and bone metabolism offers addition...

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Bibliographic Details
Main Authors: Wühl, Elke (Author) , Schaefer, Franz (Author)
Format: Article (Journal)
Language:English
Published: 2002
In: Hormone research
Year: 2002, Volume: 58, Pages: 35-38
ISSN:1423-0046
DOI:10.1159/000066480
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1159/000066480
Verlag, lizenzpflichtig, Volltext: https://www.karger.com/Article/FullText/66480
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Author Notes:Elke Wühl, Franz Schaefer
Description
Summary:Recombinant human growth hormone (GH) has proven effective in promoting growth in short children with chronic renal failure before and after renal transplantation. The action of GH and its mediator insulin-like growth factor 1 on body composition, protein, glucose and bone metabolism offers additional therapeutic options. One might be the improvement of the catabolic state in adults with end-stage renal failure. In few pilot studies and two placebo-controlled studies of 6 months duration, GH treatment in adults on dialysis showed clear anabolic effects resulting in a significant increase in lean body mass.
Item Description:Published online: November 17, 2004
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Physical Description:Online Resource
ISSN:1423-0046
DOI:10.1159/000066480