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Comparison of functional MR-venography and EPI-BOLD fMRI at 1.5 t

Functional magnetic resonance imaging (fMRI) of the brain using blood oxygenation level dependent (BOLD) contrast relies on the changes of paramagnetic deoxyhemoglobin concentration, which affects brain parenchyma and draining venous vessels. These changes in deoxyhemoglobin concentration in venous...

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Hauptverfasser: Baudendistel, Klaus (Verfasst von) , Reichenbach, Jürgen (Verfasst von) , Metzner, Roland (Verfasst von) , Schröder, Johannes (Verfasst von) , Schad, Lothar R. (Verfasst von)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 8 December 1998
In: Magnetic resonance imaging
Year: 1998, Jahrgang: 16, Heft: 8, Pages: 989-9914
ISSN:1873-5894
DOI:10.1016/S0730-725X(98)00085-X
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S0730-725X(98)00085-X
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0730725X9800085X
Volltext
Verfasserangaben:Klaus T. Baudendistel, Jürgen R. Reichenbach, Roland Metzner, Johannes Schroeder, Lothar R. Schad
Beschreibung
Zusammenfassung:Functional magnetic resonance imaging (fMRI) of the brain using blood oxygenation level dependent (BOLD) contrast relies on the changes of paramagnetic deoxyhemoglobin concentration, which affects brain parenchyma and draining venous vessels. These changes in deoxyhemoglobin concentration in venous vessels can also be monitored using a high-resolution susceptibility-based MR-venography technique. Four volunteers participated in the study in which functional MR-venograms were compared with conventional echo-planar imaging (EPI)-BOLD-fMRI. In all cases, small venous vessels could be identified close to the areas of activation detected by conventional fMRI. In the venograms, task performance (finger tapping) resulted in a loss of venous vessel contrast compared to the resting state, which is consistent with a local decrease of deoxyhemoglobin concentration. MR-venography allows a direct visualization of the BOLD-effect at high spatial resolution. In combination with conventional fMRI, this technique may help to separate the contribution of brain parenchyma and venous vessels in fMRI studies.
Beschreibung:Gesehen am 25.01.2021
Beschreibung:Online Resource
ISSN:1873-5894
DOI:10.1016/S0730-725X(98)00085-X

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