Cover Image

Comparison of functional MR-venography and EPI-BOLD fMRI at 1.5 t

Functional magnetic resonance imaging (fMRI) of the brain using blood oxygenation level dependent (BOLD) contrast relies on the changes of paramagnetic deoxyhemoglobin concentration, which affects brain parenchyma and draining venous vessels. These changes in deoxyhemoglobin concentration in venous...

Full description

Saved in:
Bibliographic Details
Main Authors: Baudendistel, Klaus (Author) , Reichenbach, Jürgen (Author) , Metzner, Roland (Author) , Schröder, Johannes (Author) , Schad, Lothar R. (Author)
Format: Article (Journal)
Language:English
Published: 8 December 1998
In: Magnetic resonance imaging
Year: 1998, Volume: 16, Issue: 8, Pages: 989-9914
ISSN:1873-5894
DOI:10.1016/S0730-725X(98)00085-X
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S0730-725X(98)00085-X
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0730725X9800085X
Get full text
Author Notes:Klaus T. Baudendistel, Jürgen R. Reichenbach, Roland Metzner, Johannes Schroeder, Lothar R. Schad
Description
Summary:Functional magnetic resonance imaging (fMRI) of the brain using blood oxygenation level dependent (BOLD) contrast relies on the changes of paramagnetic deoxyhemoglobin concentration, which affects brain parenchyma and draining venous vessels. These changes in deoxyhemoglobin concentration in venous vessels can also be monitored using a high-resolution susceptibility-based MR-venography technique. Four volunteers participated in the study in which functional MR-venograms were compared with conventional echo-planar imaging (EPI)-BOLD-fMRI. In all cases, small venous vessels could be identified close to the areas of activation detected by conventional fMRI. In the venograms, task performance (finger tapping) resulted in a loss of venous vessel contrast compared to the resting state, which is consistent with a local decrease of deoxyhemoglobin concentration. MR-venography allows a direct visualization of the BOLD-effect at high spatial resolution. In combination with conventional fMRI, this technique may help to separate the contribution of brain parenchyma and venous vessels in fMRI studies.
Item Description:Gesehen am 25.01.2021
Physical Description:Online Resource
ISSN:1873-5894
DOI:10.1016/S0730-725X(98)00085-X

Similar Items