Polydimethylsiloxane-based wide-range mass calibration for direct analysis in real-time mass spectrometry
Direct analysis in real-time mass spectrometry (DART-MS) is normally applied for small-molecule analysis up to about m/z 1,000. Here, for the analysis of polydimethylsiloxanes, high-mass capabilities expanding beyond m/z 3,000 are demonstrated. In addition, polydimethylsiloxanes provide an ideal mas...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
14 August 2013
|
| In: |
Analytical and bioanalytical chemistry
Year: 2013, Volume: 405, Issue: 26, Pages: 8663-8668 |
| ISSN: | 1618-2650 |
| DOI: | 10.1007/s00216-013-7287-1 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00216-013-7287-1
|
| Author Notes: | Jürgen H. Gross |
| Summary: | Direct analysis in real-time mass spectrometry (DART-MS) is normally applied for small-molecule analysis up to about m/z 1,000. Here, for the analysis of polydimethylsiloxanes, high-mass capabilities expanding beyond m/z 3,000 are demonstrated. In addition, polydimethylsiloxanes provide an ideal mass calibration standard for positive-ion DART-MS. A mass reference list has been compiled to cover ions from m/z 200 up to m/z 2,600. Species with more than 20 silicon atoms exhibit increasingly broader isotopic patterns with decreasing abundances of the monoisotopic ions. The use of the first isotopic peaks for analyte ions above m/z 2,000 serves as a work-around and ensures easy and reproducible recognition of the reference peaks by the instrument data system. Here, the positive-ion DART mass spectra of polydimethylsiloxanes and the corresponding experimental procedures are described, and the mass reference list is provided. |
|---|---|
| Item Description: | Gesehen am 29.01.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1618-2650 |
| DOI: | 10.1007/s00216-013-7287-1 |