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Recognition of glycosaminoglycan chemical patterns using an unbiased sensor array

A sensor array composed of eight functionalized gold nanoparticles and a fluorescent polymer was utilized to identify 11 glycosaminoglycans (GAGs) by their chemical signatures. Particle ligand structure was key in differentiating analytes, with aromatic and specific sugar functionalities recognizing...

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Bibliographische Detailangaben
Hauptverfasser: Elci, S. Gokhan (VerfasserIn) , Moyano, Daniel F. (VerfasserIn) , Rana, Subinoy (VerfasserIn) , Tonga, Gulen Yesilbag (VerfasserIn) , Phillips, Ronnie L. (VerfasserIn) , Bunz, Uwe H. F. (VerfasserIn) , Rotello, Vincent M. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2 April 2013
In: Chemical science
Year: 2013, Jahrgang: 4, Heft: 5, Pages: 2076-2080
ISSN:2041-6539
DOI:10.1039/C3SC22279A
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1039/C3SC22279A
Verlag, lizenzpflichtig, Volltext: https://pubs.rsc.org/en/content/articlelanding/2013/sc/c3sc22279a
Volltext
Verfasserangaben:S. Gokhan Elci, Daniel F. Moyano, Subinoy Rana, Gulen Yesilbag Tonga, Ronnie L. Phillips, Uwe H. F. Bunz and Vincent M. Rotello
Beschreibung
Zusammenfassung:A sensor array composed of eight functionalized gold nanoparticles and a fluorescent polymer was utilized to identify 11 glycosaminoglycans (GAGs) by their chemical signatures. Particle ligand structure was key in differentiating analytes, with aromatic and specific sugar functionalities recognizing GAG structural parameters including sulfonation, acetylation, epimeric structure, size, and charge.
Beschreibung:Gesehen am 01.02.2021
Beschreibung:Online Resource
ISSN:2041-6539
DOI:10.1039/C3SC22279A

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