RNA Exosome
Assembling work by prominent researchers in the field of RNA exosomes, this excellent introduction to the fascinating protein complex provides a comprehensive account of the proteins' many functions as well as a historical account of the field's development.
Gespeichert in:
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| Dokumenttyp: | Book/Monograph |
| Sprache: | Englisch |
| Veröffentlicht: |
New York, NY
Springer New York
2010
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| Schriftenreihe: | Advances in experimental medicine and biology
volume 702 |
| In: |
Advances in experimental medicine and biology (volume 702)
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| Volumes / Articles: | Show Volumes / Articles. |
| Online-Zugang: | Aggregator, lizenzpflichtig: https://ebookcentral.proquest.com/lib/kxp/detail.action?docID=763681
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| Verfasserangaben: | editors: Torben Heick Jensen |
| Zusammenfassung: | Assembling work by prominent researchers in the field of RNA exosomes, this excellent introduction to the fascinating protein complex provides a comprehensive account of the proteins' many functions as well as a historical account of the field's development. Intro -- Title Page -- Copyright Page -- PREFACE -- ABOUT THE EDITOR... -- PARTICIPANTS -- Table of Contents -- CHAPTER 1 FINDING THE EXOSOME -- Abstract -- INTRODUCTION -- FROM NORTHERNS TO NUCLEASES -- A GLIMPSE OF THE EXOSOME -- THE COMPLETE COMPLEX -- A BROADER PERSPECTIVE -- CONCLUSION -- ACKNOWLEDGEMENTS -- REFERENCES -- CHAPTER 2 STRUCTURAL COMPONENTS AND ARCHITECTURES OF RNA EXOSOMES -- Abstract -- INTRODUCTION -- GLOBAL STRUCTURE OF THE EXOSOME -- RNase PH-LIKE DOMAINS IN BACTERIAL, ARCHAEAL AND EUKARYOTIC CORE EXOSOMES -- S1 AND KH CONTAINING DOMAINS IN BACTERIAL, ARCHAEAL AND EUKARYOTIC CORE EXOSOMES -- MECHANISM OF PHOSPHOROLYTIC ACTIVITY IN BACTERIAL PNPase AND ARCHAEAL EXOSOMES -- Rrp44, A EUKARYOTIC EXOSOME SUBUNIT WITH HYDROLYTIC ENDORIBONUCLEASE AND PROCESSIVE EXORIBONUCLEASE ACTIVITIES -- Rrp44 PIN DOMAIN -- Rrp44 RNB DOMAIN -- Rrp44 AND THE 10-COMPONENT EXOSOME -- Rrp6, A EUKARYOTIC EXOSOME SUBUNIT WITH DISTRIBUTIVE HYDROLYTIC ACTIVITIES -- Rrp6 INTERACTIONS WITH THE EXOSOME CORE -- CONCLUSION -- ACKNOWLEDGEMENTS -- REFERENCES -- CHAPTER 3 THE ARCHAEAL EXOSOME -- Abstract -- INTRODUCTION -- CORE SUBUNITS OF THE ARCHAEAL EXOSOME -- STRUCTURE AND MECHANISM -- The Catalytically Active RPD-Hexamer -- The Flexible RNA-Binding Cap -- PHYSIOLOGICAL FUNCTIONS -- CONCLUSION -- ACKNOWLEDGEMENTS -- NOTE ADDED IN PROOF -- REFERENCES -- CHAPTER 4 THE EXOSOMES OF TRYPANOSOMES AND OTHER PROTISTS -- Abstract -- INTRODUCTION -- TRYPANOSOMES AS A MODEL SYSTEM FOR RNA PROCESSING AND TURNOVER -- THE STRUCTURE OF THE TRYPANOSOME EXOSOME -- THE POSITION OF RRP6 RELATIVE TO THE EXOSOME CORE -- FUNCTIONS OF THE TRYPANOSOME EXOSOME IN THE NUCLEUS -- FUNCTIONS OF THE TRYPANOSOME EXOSOME IN THE CYTOPLASM -- CONSERVATION OF THE EXOSOME IN EUKARYOTIC EVOLUTION -- CONCLUSION -- ACKNOWLEDGEMENTS -- REFERENCES. |
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| Beschreibung: | Description based on publisher supplied metadata and other sources |
| Beschreibung: | Online Resource |
| ISBN: | 9781441978417 |