Interaction of JAK with steroid receptor function
The function of steroid receptors is not only regulated by steroid hormones, but also by multiple cellular signaling cascades activated by membrane-bound receptors which are stimulated by growth factors or cytokines. Cross-talk between JAK and steroid receptors plays a central role in the regulation...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
07 May 2013
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| In: |
JAK-STAT
Year: 2013, Volume: 2, Issue: 4 |
| ISSN: | 2162-3996 |
| DOI: | 10.4161/jkst.24911 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.4161/jkst.24911
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| Author Notes: | Nibedita Gupta and Doris Mayer |
| Summary: | The function of steroid receptors is not only regulated by steroid hormones, but also by multiple cellular signaling cascades activated by membrane-bound receptors which are stimulated by growth factors or cytokines. Cross-talk between JAK and steroid receptors plays a central role in the regulation of a multitude of physiological processes and aberrant signaling is involved in the development of numerous diseases including cancer. In this review we provide a brief summary of the knowledge of interactions between JAK and the function of steroid receptors in normal cells and tissues and in diseases. |
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| Item Description: | Gesehen am 10.02.2021 |
| Physical Description: | Online Resource |
| ISSN: | 2162-3996 |
| DOI: | 10.4161/jkst.24911 |