Subsequent gene expression pattern in dendritic cells following multiple trauma
Major trauma initiates a systemic inflammatory response, which is characterized by systemic release of various chemokines. There is growing evidence for the extraordinary role of dendritic cells (DC) as professional antigen-presenting cells and activators of the immune response. Recently, the impact...
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| Main Authors: | , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2013
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| In: |
Langenbeck's archives of surgery
Year: 2012, Volume: 398, Issue: 2, Pages: 327-333 |
| ISSN: | 1435-2451 |
| DOI: | 10.1007/s00423-012-1031-8 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00423-012-1031-8
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| Author Notes: | Emanuel V. Geiger, Marcus Maier, Serin Schiessling, Sebastian Wutzler, Mark Lehnert, Ingo Marzi, Dirk Henrich |
| Summary: | Major trauma initiates a systemic inflammatory response, which is characterized by systemic release of various chemokines. There is growing evidence for the extraordinary role of dendritic cells (DC) as professional antigen-presenting cells and activators of the immune response. Recently, the impact of severe trauma on DC transcriptomic activation was demonstrated. The purpose of the present study was to evaluate gene expression pattern in DC following multiple trauma to gain further understanding of the mechanisms of posttraumatic immune response. |
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| Item Description: | Gesehen am 03.02.2020 First published: 22 November 2012 |
| Physical Description: | Online Resource |
| ISSN: | 1435-2451 |
| DOI: | 10.1007/s00423-012-1031-8 |