Pylorus resection or pylorus preservation in partial pancreatico-duodenectomy (PROPP study): study protocol for a randomized controlled trial

Partial pancreatico-duodenectomy (PD) is the standard treatment for tumors of the pancreatic head. Today, preservation of the pylorus has been widely accepted as the surgical standard in this procedure. A common postoperative complication is the occurrence of delayed gastric emptying (DGE), which ca...

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Main Authors: Hackert, Thilo (Author) , Bruckner, Thomas (Author) , Dörr-Harim, Colette (Author) , Diener, Markus K. (Author) , Knebel, Phillip (Author) , Hartwig, Werner (Author) , Strobel, Oliver (Author) , Fritz, Stefan (Author) , Schneider, Lutz (Author) , Werner, Jens (Author) , Büchler, Markus W. (Author)
Format: Article (Journal)
Language:English
Published: 14 February 2013
In: Trials
Year: 2013, Volume: 14
ISSN:1468-6694
DOI:10.1186/1745-6215-14-44
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1745-6215-14-44
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Author Notes:Thilo Hackert, Thomas Bruckner, Colette Dörr-Harim, Markus K. Diener, Phillip Knebel, Werner Hartwig, Oliver Strobel, Stefan Fritz, Lutz Schneider, Jens Werner and Markus W. Büchler
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Summary:Partial pancreatico-duodenectomy (PD) is the standard treatment for tumors of the pancreatic head. Today, preservation of the pylorus has been widely accepted as the surgical standard in this procedure. A common postoperative complication is the occurrence of delayed gastric emptying (DGE), which causes impairment of oral intake andpatients’ quality of life, prolongation of hospital stay and delay of further treatment (for example adjuvant chemotherapy). In a small number of two retrospective and one randomized studies, a modification by resection of the pylorus with preservation of the stomach has shown to reduce DGE incidence. The aim of the present study is to investigate the effect of pylorus resection on postoperative DGE in PD
Item Description:Gesehen am 09.02.2021
Physical Description:Online Resource
ISSN:1468-6694
DOI:10.1186/1745-6215-14-44