In vitro drug sensitivity predicts response and survival after individualized sensitivity-directed chemotherapy in metastatic melanoma: a multicenter phase II trial of the Dermatologic Cooperative Oncology Group

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Purpose:In vitro sensitivity assays are promising tools to predict the individual outcome of different chemotherapy regimens. However, a direct association between in vitro and in vivo chemosensitivity has to be shown by clinical studies. This multicenter phase II trial was aimed to investigate the...

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Bibliographic Details
Main Authors:	Ugurel, Selma (Author) , Schadendorf, Dirk (Author) , Figl, Adina (Author) , Rittgen, Werner (Author) , Delorme, Stefan (Author)
Format:	Article (Journal)
Language:	English
Published:	September 25, 2006
In:	Clinical cancer research Year: 2006, Volume: 12, Issue: 18, Pages: 5454-5463
ISSN:	1557-3265
DOI:	10.1158/1078-0432.CCR-05-2763
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1158/1078-0432.CCR-05-2763 Verlag, lizenzpflichtig, Volltext: https://clincancerres.aacrjournals.org/content/12/18/5454
Author Notes:	Selma Ugurel, Dirk Schadendorf, Claudia Pföhler, Karsten Neuber, Adina Thoelke, Jens Ulrich, Axel Hauschild, Konstanze Spieth, Martin Kaatz, Werner Rittgen, Stefan Delorme, Wolfgang Tilgen, and Uwe Reinhold

Dacarbazine, Cisplatin, and Interferon-alfa-2b with or without Interleukin-2 in metastatic melanoma: a randomized phase III trial (18951) of the European Organisation for Research... by Keilholz, Ulrich (Author) , Schadendorf, Dirk (Author) ,

in: Journal of clinical oncology, 23 (2005), 27, Seite 6747-6755

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Prospective randomized trial of interferon Alfa-2b and Interleukin-2 as adjuvant treatment for resected intermediate- and high-risk primary melanoma without clinically detectable n... by Hauschild, Axel (Author) , Schadendorf, Dirk (Author) ,

in: Journal of clinical oncology, 21 (2003), 15, Seite 2883-2888

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Patterns of constitutive and IFN-γ inducible expression of HLA class II molecules in human melanoma cell lines by Rodríguez, Teresa (Author) , Méndez, Roman (Author) , Schadendorf, Dirk (Author) ,

in: Immunogenetics, 59 (2007,2) Artikelnummer 123, 11 Seiten

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Differences in global gene expression in melanoma cell lines with and without homozygous deletion of the CDKN2A locus genes by Blöthner, Sandra (Author) , Hemminki, Kari (Author) , Chen, Bowang (Author) , Ugurel, Selma (Author) , Schadendorf, Dirk (Author) , Kumar, Rajiv (Author) ,

in: Melanoma research, 16 (2006), 4, Seite 297-307

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Dose-intensified bi-weekly temozolomide in patients with asymptomatic brain metastases from malignant melanoma: a phase II DeCOG/ADO study by Schadendorf, Dirk (Author) , Ugurel, Selma (Author) , Figl, Adina (Author) ,

in: Annals of oncology, 17 (2006), 10, Seite 1592-1597

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Tumor type M2 pyruvate kinase (TuM2-PK) as a novel plasma tumor marker in melanoma by Ugurel, Selma (Author) , Sucker, Antje (Author) , Rittgen, Werner (Author) , Schadendorf, Dirk (Author) ,

in: International journal of cancer, 117 (2005), 5, Seite 825-830

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Clinical phase II study of pegylated liposomal doxorubicin as second-line treatment in disseminated melanoma by Fink, Wolfram (Author) , Figl, Adina (Author) , Figl, Robert (Author) , Ugurel, Selma (Author) , Schadendorf, Dirk (Author) ,

in: Onkologie, 27 (2004), 6, Seite 540-544

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Down-regulation of HLA class II and costimulatory CD86/B7-2 on circulating monocytes from melanoma patients by Ugurel, Selma (Author) , Schadendorf, Dirk (Author) ,

in: Cancer immunology immunotherapy, 53 (2004), 6, Seite 551-559

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Identification of known and novel immunogenic T-cell epitopes from tumor antigens recognized by peripheral blood T cells from patients responding to IL-2-based treatment by Scheibenbogen, Carmen (Author) , Song, Mingxia (Author) , Schadendorf, Dirk (Author) ,

in: International journal of cancer, 98 (2002), 3, Seite 409-414

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Treatment of disseminated ocular melanoma with sequential fotemustine, interferon α, and interleukin 2 by Becker, Jürgen C. (Author) , Schadendorf, Dirk (Author) ,

in: British journal of cancer, 87 (2002), 8, Seite 840-845

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