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Current challenges in the post-transplant care of liver transplant recipients in Germany

Improving long-term patient and graft survival after liver transplantation (LT) remains a major challenge. Compared to the early phase after LT, long-term morbidity and mortality of the recipients not only depends on complications immediately related to the graft function, infections, or rejection,...

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Main Authors: Herzer, Kerstin (Author) , Sterneck, Martina (Author) , Welker, Martin-Walter (Author) , Nadalin, Silvio (Author) , Kirchner, Gabriele (Author) , Braun, Felix (Author) , Malessa, Christina (Author) , Herber, Adam (Author) , Pratschke, Johann (Author) , Weiss, Karl Heinz (Author) , Jäckel, Elmar (Author) , Tacke, Frank (Author)
Format: Article (Journal)
Language:English
Published: 5 November 2020
In: Journal of Clinical Medicine
Year: 2020, Volume: 9, Issue: 11
ISSN:2077-0383
DOI:10.3390/jcm9113570
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/jcm9113570
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2077-0383/9/11/3570
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Author Notes:Kerstin Herzer, Martina Sterneck, Martin-Walter Welker, Silvio Nadalin, Gabriele Kirchner, Felix Braun, Christina Malessa, Adam Herber, Johann Pratschke, Karl Heinz Weiss, Elmar Jaeckel and Frank Tacke
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Summary:Improving long-term patient and graft survival after liver transplantation (LT) remains a major challenge. Compared to the early phase after LT, long-term morbidity and mortality of the recipients not only depends on complications immediately related to the graft function, infections, or rejection, but also on medical factors such as de novo malignancies, metabolic disorders (e.g., new-onset diabetes, osteoporosis), psychiatric conditions (e.g., anxiety, depression), renal failure, and cardiovascular diseases. While a comprehensive post-transplant care at the LT center and the connected regional networks may improve outcome, there is currently no generally accepted standard to the post-transplant management of LT recipients in Germany. We therefore described the structure and standards of post-LT care by conducting a survey at 12 German LT centers including transplant hepatologists and surgeons. Aftercare structures and form of cost reimbursement considerably varied between LT centers across Germany. Further discussions and studies are required to define optimal structure and content of post-LT care systems, aiming at improving the long-term outcomes of LT recipients.
Item Description:Gesehen am 05.02.2021
Physical Description:Online Resource
ISSN:2077-0383
DOI:10.3390/jcm9113570

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