Exercise and lung cancer surgery: a systematic review of randomized-controlled trials

Lung cancer patients undergoing surgery are often left physically deconditioned and/or with functional deficits. Exercise interventions may improve pulmonary and physical function before and after lung resection. We conducted a systematic review of randomized-controlled trials (RCTs) testing the imp...

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Main Authors: Himbert, Caroline (Author) , Klossner, Nicole (Author) , Coletta, Adriana M. (Author) , Barnes, Christopher A. (Author) , Wiskemann, Joachim (Author) , LaStayo, Paul C. (Author) , Varghese Jr., Thomas K. (Author) , Ulrich, Cornelia (Author)
Format: Article (Journal)
Language:English
Published: 13 September 2020
In: Critical reviews in oncology, hematology
Year: 2020, Volume: 156, Pages: 1-12
ISSN:1879-0461
DOI:10.1016/j.critrevonc.2020.103086
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.critrevonc.2020.103086
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1040842820302225
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Author Notes:Caroline Himbert, Nicole Klossner, Adriana M. Coletta, Christopher A. Barnes, Joachim Wiskemann, Paul C. LaStayo, Thomas K. Varghese Jr., Cornelia M. Ulrich
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Summary:Lung cancer patients undergoing surgery are often left physically deconditioned and/or with functional deficits. Exercise interventions may improve pulmonary and physical function before and after lung resection. We conducted a systematic review of randomized-controlled trials (RCTs) testing the impact of pre-, post-, and combined pre-and-post surgery exercise interventions on physical and pulmonary function in lung cancer patients. Exercise pre-surgery seems to substantially improve physical and pulmonary function, which are factors associated with improved ability to undergo surgery while reducing post-surgery complications. Evidence is inconsistent for post-surgery interventions, reporting no or moderate effects. Results from pre-and-post surgery interventions are limited to one study. In conclusion, pre- and post-surgery exercise interventions, individually, have shown beneficial effects for lung cancer patients undergoing surgery. The impact of interventions combining both pre- and post-surgery exercise programs remains unknown. More evidence is needed on the ideal exercise setting, and timing across the lung cancer care continuum.
Item Description:Gesehen am 16.02.2021
Physical Description:Online Resource
ISSN:1879-0461
DOI:10.1016/j.critrevonc.2020.103086