Cover Image

PRediction of acute coronary syndrome in acute ischemic StrokE (PRAISE) - protocol of a prospective, multicenter trial with central reading and predefined endpoints

Current guidelines recommend measurement of troponin in acute ischemic stroke (AIS) patients. In AIS patients, troponin elevation is associated with increased mortality and worse outcome. However, uncertainty remains regarding the underlying pathophysiology of troponin elevation after stroke, partic...

Full description

Saved in:
Bibliographic Details
Main Authors: Nolte, Christian H. (Author) , Rennenberg, Regina von (Author) , Litmeier, Simon (Author) , Scheitz, Jan Friedrich (Author) , Leistner, David (Author) , Blankenberg, Stephan (Author) , Dichgans, Martin (Author) , Katus, Hugo (Author) , Petzold, Gabor C. (Author) , Pieske, Burkert (Author) , Regitz-Zagrosek, Vera (Author) , Wegscheider, Karl (Author) , Zeiher, Andreas M. (Author) , Landmesser, Ulf (Author) , Endres, Matthias (Author)
Format: Article (Journal)
Language:English
Published: 27 August 2020
In: BMC neurology
Year: 2020, Volume: 20, Pages: 318
ISSN:1471-2377
DOI:10.1186/s12883-020-01903-0
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12883-020-01903-0
Verlag, lizenzpflichtig, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450553
Get full text
Author Notes:Christian H. Nolte, Regina von Rennenberg, Simon Litmeier, Jan F. Scheitz, David M. Leistner, Stephan Blankenberg, Martin Dichgans, Hugo Katus, Gabor C. Petzold, Burkert Pieske, Vera Regitz-Zagrosek, Karl Wegscheider, Andreas M. Zeiher, Ulf Landmesser, Matthias Endres
Description
Summary:Current guidelines recommend measurement of troponin in acute ischemic stroke (AIS) patients. In AIS patients, troponin elevation is associated with increased mortality and worse outcome. However, uncertainty remains regarding the underlying pathophysiology of troponin elevation after stroke, particularly regarding diagnostic and therapeutic consequences. Troponin elevation may be caused by coronary artery disease (CAD) and more precisely acute coronary syndrome (ACS). Both have a high prevalence in stroke patients and contribute to poor outcome. Therefore, better diagnostic algorithms are needed to identify those AIS patients likely to have ACS or other manifestations of CAD.
Item Description:Gesehen am 16.02.2021
Physical Description:Online Resource
ISSN:1471-2377
DOI:10.1186/s12883-020-01903-0

Similar Items