Adapters in lymphocyte signalling
Adapter proteins are well recognised as important molecular switches connecting immunoreceptors with intracellular signalling pathways. However, recent data suggest that homeostasis within the lymphatic system also depends on the coordinated activities of negative regulatory adapter proteins. These...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2001
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| In: |
Current opinion in immunology
Year: 2001, Volume: 13, Issue: 3, Pages: 307-316 |
| ISSN: | 1879-0372 |
| DOI: | 10.1016/s0952-7915(00)00220-x |
| Online Access: | Verlag, lizenzpflichtig, Volltext: http://doi.org/10.1016/s0952-7915(00)00220-x
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| Author Notes: | Albrecht Leo, Burkhart Schraven |
| Summary: | Adapter proteins are well recognised as important molecular switches connecting immunoreceptors with intracellular signalling pathways. However, recent data suggest that homeostasis within the lymphatic system also depends on the coordinated activities of negative regulatory adapter proteins. These prevent activation of lymphocytes in the absence of externally applied signals and regulate termination/limitation of ongoing immune responses via different mechanisms. |
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| Item Description: | Gesehen am 19.02.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1879-0372 |
| DOI: | 10.1016/s0952-7915(00)00220-x |