Different culture media affect growth characteristics, surface marker distribution and chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells

Bone marrow-derived mesenchymal stromal cells (BM-MSCs) play an important role in modern tissue engineering, while distinct variations of culture media compositions and supplements have been reported. Because MSCs are heterogeneous regarding their regenerative potential and their surface markers, th...

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Main Authors: Hagmann, Sébastien (Author) , Moradi, Babak (Author) , Frank, Sebastian (Author) , Dreher, Thomas (Author) , Richter, Wiltrud (Author) , Gotterbarm, Tobias (Author)
Format: Article (Journal)
Language:English
Published: 30 July 2013
In: BMC musculoskeletal disorders
Year: 2013, Volume: 14
ISSN:1471-2474
DOI:10.1186/1471-2474-14-223
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2474-14-223
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Author Notes:Sebastien Hagmann, Babak Moradi, Sebastian Frank, Thomas Dreher, Peer Wolfgang Kämmerer, Wiltrud Richter and Tobias Gotterbarm
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Summary:Bone marrow-derived mesenchymal stromal cells (BM-MSCs) play an important role in modern tissue engineering, while distinct variations of culture media compositions and supplements have been reported. Because MSCs are heterogeneous regarding their regenerative potential and their surface markers, these parameters were compared in four widely used culture media compositions.
Item Description:Gesehen am 15.10.2021
Physical Description:Online Resource
ISSN:1471-2474
DOI:10.1186/1471-2474-14-223