Derangement of apoptosis in cancer
Cancer results when cells grow faster and live longer than normal. Therefore increased - activity of antiapoptotic proteins or decreased activity of proapoptotic proteins - can contribute to the development of cancer. Much progress has been made in the understanding - of how these changes occur. The...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
August 04, 2001
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| In: |
The lancet
Year: 2001, Volume: 358, Issue: 9279, Pages: 345-346 |
| DOI: | 10.1016/S0140-6736(01)05584-2 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S0140-6736(01)05584-2 Verlag, lizenzpflichtig, Volltext: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(01)05584-2/abstract 
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| Author Notes: | Sören T. Eichhorst, Peter H. Krammer |
| Summary: | Cancer results when cells grow faster and live longer than normal. Therefore increased - activity of antiapoptotic proteins or decreased activity of proapoptotic proteins - can contribute to the development of cancer. Much progress has been made in the understanding - of how these changes occur. The importance of such knowledge is that inactivation - of apoptotic pathways may lead not only to the accumulation of cells but also to inability - of cells to respond to potentially harmful mutations, DNA damage, or chemotherapeutic - drugs. |
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| Item Description: | Gesehen am 03.03.2021 |
| Physical Description: | Online Resource |
| DOI: | 10.1016/S0140-6736(01)05584-2 |