Genome-wide association studies identify four ER negative-specific breast cancer risk loci
Montserrat Garcia-Closas and colleagues report a meta-analysis of three genome-wide association studies for estrogen receptor (ER)-negative breast cancer, including 4,193 ER-negative breast cancer cases and 35,194 controls, with replication using the iCOGS custom genotyping array in 40 studies, incl...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
27 March 2013
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| In: |
Nature genetics
Year: 2013, Jahrgang: 45, Heft: 4, Pages: 392-398 |
| ISSN: | 1546-1718 |
| DOI: | 10.1038/ng.2561 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/ng.2561 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/ng.2561 |
| Verfasserangaben: | Montserrat Garcia-Closas, Jenny Chang-Claude, Barbara Burwinkel, Hermann Brenner, Ute Hamann, Federick Marme, Andreas Schneeweiss, Christof Sohn, Heiko Müller, Volker Arndt, Rebecca Hein, Rudolf Kaaks, Federico Canzian [und viele weitere] |
| Zusammenfassung: | Montserrat Garcia-Closas and colleagues report a meta-analysis of three genome-wide association studies for estrogen receptor (ER)-negative breast cancer, including 4,193 ER-negative breast cancer cases and 35,194 controls, with replication using the iCOGS custom genotyping array in 40 studies, including 6,514 cases and 41,455 controls. They identify four loci associated with ER-negative but not ER-positive breast cancer. |
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| Beschreibung: | Gesehen am 03.03.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1546-1718 |
| DOI: | 10.1038/ng.2561 |