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Genome-wide association studies identify four ER negative-specific breast cancer risk loci

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Montserrat Garcia-Closas and colleagues report a meta-analysis of three genome-wide association studies for estrogen receptor (ER)-negative breast cancer, including 4,193 ER-negative breast cancer cases and 35,194 controls, with replication using the iCOGS custom genotyping array in 40 studies, incl...

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Main Authors: Garcia-Closas, Montserrat (Author) , Chang-Claude, Jenny (Author) , Burwinkel, Barbara (Author) , Brenner, Hermann (Author) , Hamann, Ute (Author) , Marmé, Frederik (Author) , Schneeweiss, Andreas (Author) , Sohn, Christof (Author) , Müller, Heiko (Author) , Arndt, Volker (Author) , Hein, Rebecca (Author) , Kaaks, Rudolf (Author) , Canzian, Federico (Author)
Format: Article (Journal)
Language:English
Published: 27 March 2013
In: Nature genetics
Year: 2013, Volume: 45, Issue: 4, Pages: 392-398
ISSN:1546-1718
DOI:10.1038/ng.2561
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/ng.2561
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/ng.2561
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Author Notes:Montserrat Garcia-Closas, Jenny Chang-Claude, Barbara Burwinkel, Hermann Brenner, Ute Hamann, Federick Marme, Andreas Schneeweiss, Christof Sohn, Heiko Müller, Volker Arndt, Rebecca Hein, Rudolf Kaaks, Federico Canzian [und viele weitere]
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Summary:Montserrat Garcia-Closas and colleagues report a meta-analysis of three genome-wide association studies for estrogen receptor (ER)-negative breast cancer, including 4,193 ER-negative breast cancer cases and 35,194 controls, with replication using the iCOGS custom genotyping array in 40 studies, including 6,514 cases and 41,455 controls. They identify four loci associated with ER-negative but not ER-positive breast cancer.
Item Description:Gesehen am 03.03.2020
Physical Description:Online Resource
ISSN:1546-1718
DOI:10.1038/ng.2561

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