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Prognostic value of histamine H1 receptor expression in oral squamous cell carcinoma

Overexpression of the histamine H1 receptor (H1R) has been described in a variety of tumor models, but experience in oral squamous cell carcinomas (OSCC) is not available. Current adjuvant treatment options for OSCC can be improved by the identification of new targets of therapy. Herein, we evaluate...

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Main Authors: Grimm, Martin (Author) , Krimmel, Michael Fred (Author) , Alexander-Friedrich, Dorothea (Author) , Munz, Adelheid (Author) , Kluba, Susanne (Author) , Keutel, Constanze (Author) , Hoffmann, Jürgen (Author) , Polligkeit, Joachim (Author) , Reinert, Siegmar (Author) , Hoefert, Sebastian (Author)
Format: Article (Journal)
Language:English
Published: 2013
In: Clinical oral investigations
Year: 2012, Volume: 17, Issue: 3, Pages: 949-955
ISSN:1436-3771
DOI:10.1007/s00784-012-0784-3
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00784-012-0784-3
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Author Notes:Martin Grimm, Michael Krimmel, Dorothea Alexander, Adelheid Munz, Susanne Kluba, Constanze Keutel, Juergen Hoffmann, Joachim Polligkeit, Siegmar Reinert, Sebastian Hoefert
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Summary:Overexpression of the histamine H1 receptor (H1R) has been described in a variety of tumor models, but experience in oral squamous cell carcinomas (OSCC) is not available. Current adjuvant treatment options for OSCC can be improved by the identification of new targets of therapy. Herein, we evaluated H1R expression in a large patient cohort of OSCC.
Item Description:Gesehen am 10.03.2021
First published: 11 July 2012
Physical Description:Online Resource
ISSN:1436-3771
DOI:10.1007/s00784-012-0784-3

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