The future of targeted peptidomics

Targeted MS is becoming increasingly important for sensitive and specific quantitative detection of proteins and respective PTMs. In this article, Ceglarek et al. [Proteomics Clin. Appl. 2013, 7, 794-801] present an LC-MS-based method for simultaneous quantitation of seven apolipoproteins in serum s...

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Bibliographic Details
Main Author: Findeisen, Peter (Author)
Format: Article (Journal)
Language:English
Published: 12 November 2013
In: Proteomics. Clinical applications
Year: 2013, Volume: 7, Issue: 11/12, Pages: 721-722
ISSN:1862-8354
DOI:https://doi.org/10.1002/prca.201300116
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/https://doi.org/10.1002/prca.201300116
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/prca.201300116
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Author Notes:Peter Findeisen
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Summary:Targeted MS is becoming increasingly important for sensitive and specific quantitative detection of proteins and respective PTMs. In this article, Ceglarek et al. [Proteomics Clin. Appl. 2013, 7, 794-801] present an LC-MS-based method for simultaneous quantitation of seven apolipoproteins in serum specimens. The assay fulfills many necessities of routine diagnostic applications, namely, low cost, high throughput, and good reproducibility. We anticipate that validation of new biomarkers will speed up with this technology and the palette of laboratory-based diagnostic tools will hopefully be augmented significantly in the near future.
Item Description:Gesehen am 15.03.2021
Physical Description:Online Resource
ISSN:1862-8354
DOI:https://doi.org/10.1002/prca.201300116