The future of targeted peptidomics
Targeted MS is becoming increasingly important for sensitive and specific quantitative detection of proteins and respective PTMs. In this article, Ceglarek et al. [Proteomics Clin. Appl. 2013, 7, 794-801] present an LC-MS-based method for simultaneous quantitation of seven apolipoproteins in serum s...
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| Autore principale: | |
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| Natura: | Article (Journal) |
| Lingua: | inglese |
| Pubblicazione: |
12 November 2013
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| In: |
Proteomics. Clinical applications
Year: 2013, Volume: 7, Fascicolo: 11/12, Pages: 721-722 |
| ISSN: | 1862-8354 |
| DOI: | https://doi.org/10.1002/prca.201300116 |
| Accesso online: | Verlag, lizenzpflichtig, Volltext: https://doi.org/https://doi.org/10.1002/prca.201300116 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/prca.201300116 
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| Note sull'autore: | Peter Findeisen |
| Riassunto: | Targeted MS is becoming increasingly important for sensitive and specific quantitative detection of proteins and respective PTMs. In this article, Ceglarek et al. [Proteomics Clin. Appl. 2013, 7, 794-801] present an LC-MS-based method for simultaneous quantitation of seven apolipoproteins in serum specimens. The assay fulfills many necessities of routine diagnostic applications, namely, low cost, high throughput, and good reproducibility. We anticipate that validation of new biomarkers will speed up with this technology and the palette of laboratory-based diagnostic tools will hopefully be augmented significantly in the near future. |
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| Descrizione del documento: | Gesehen am 15.03.2021 |
| Descrizione fisica: | Online Resource |
| ISSN: | 1862-8354 |
| DOI: | https://doi.org/10.1002/prca.201300116 |