Impact of sex in stroke thrombolysis: a coarsened exact matching study

It is not established whether sex influences outcome and safety following intravenous thrombolysis (IVT) in acute stroke. As a significant imbalance exists between the baseline conditions of women and men, regression analysis alone may be subject to bias. Here we aimed to overcome this methodical sh...

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Bibliographic Details
Main Authors: Hametner, Christian (Author) , Kellert, Lars (Author) , Ringleb, Peter A. (Author)
Format: Article (Journal)
Language:English
Published: 10 February 2015
In: BMC neurology
Year: 2015, Volume: 15, Pages: 1-6
ISSN:1471-2377
DOI:10.1186/s12883-015-0262-z
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12883-015-0262-z
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Author Notes:Christian Hametner, Lars Kellert and Peter Arthur Ringleb
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Summary:It is not established whether sex influences outcome and safety following intravenous thrombolysis (IVT) in acute stroke. As a significant imbalance exists between the baseline conditions of women and men, regression analysis alone may be subject to bias. Here we aimed to overcome this methodical shortcoming by balancing both groups using coarsened exact matching (CEM) before evaluating outcome.
Item Description:Gesehen am 25.03.2021
Physical Description:Online Resource
ISSN:1471-2377
DOI:10.1186/s12883-015-0262-z