Pseudoautosomal repeat displays higher variability in Blacks than in Caucasians

DNA patterns from a pseudoautosomal variable number tandem repeat-like minisatellite (locus DXYS20) were compared in two samples: a Caucasian and a Black sample. We defined 3 types of DNA patterns named A, B and C, and found that these patterns have different frequencies in the Caucasian and Black g...

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Bibliographic Details
Main Authors: Rappold, Gudrun (Author) , Henke, Anja (Author) , Pohlschmid, Marita (Author) , Huisman, Titus H. J. (Author)
Format: Article (Journal)
Language:English
Published: 01 March 1992
In: Human genetics
Year: 1992, Volume: 88, Issue: 5, Pages: 573-578
ISSN:1432-1203
DOI:10.1007/BF00219347
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/BF00219347
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Author Notes:Gudrun A. Rappold, Anja Henke, Marita Pohlschmid, Titus H.J. Huisman
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Summary:DNA patterns from a pseudoautosomal variable number tandem repeat-like minisatellite (locus DXYS20) were compared in two samples: a Caucasian and a Black sample. We defined 3 types of DNA patterns named A, B and C, and found that these patterns have different frequencies in the Caucasian and Black groups. A set of alleles (the C group) in 48% of the Black sample is not found in the Caucasian sample. We also found a greater degree of fragment-size variability among Black individuals than among those of Caucasian origin. The large degree of ethnic variation indicates that this locus will be useful in population genetic studies.
Item Description:Gesehen am 06.04.2021
Physical Description:Online Resource
ISSN:1432-1203
DOI:10.1007/BF00219347