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Cerebral cavernous malformations: from CCM genes to endothelial cell homeostasis

Cerebral cavernous malformations (CCMs) are vascular lesions that can occur sporadically or as a consequence of inherited loss-of-function mutations, predominantly in the genes CCM1 (KRIT1), CCM2 (MGC4607, OSM, Malcavernin), or CCM3 (PDCD10, TFAR15). Inherited, familial CCM is characterized by the d...

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Main Authors: Fischer, Andreas (Author) , Zalvide, Juan (Author) , Faurobert, Eva (Author) , Albiges-Rizo, Corinne (Author) , Tournier-Lasserve, Elisabeth (Author)
Format: Article (Journal)
Language:English
Published: May 1, 2013
In: Trends in molecular medicine
Year: 2013, Volume: 19, Issue: 5, Pages: 302-308
ISSN:1471-499X
DOI:10.1016/j.molmed.2013.02.004
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.molmed.2013.02.004
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1471491413000336
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Author Notes:Andreas Fischer, Juan Zalvide, Eva Faurobert, Corinne Albiges-Rizo, and Elisabeth Tournier-Lasserve

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