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Clinical results of fibroblast activation protein (FAP) specific PET for non-malignant indications: systematic review

Small molecules targeting fibroblast activation protein (FAP) have emerged as a new group of tracers for positron emission tomography (PET) in 2018. While most of the existing literature has been focussed on the application of FAP-specific PET in various kinds of cancers, some researchers have, both...

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Main Authors: Windisch, Paul (Author) , Zwahlen, Daniel R. (Author) , Giesel, Frederik L. (Author) , Scholz, Eberhard P. (Author) , Lugenbiel, Patrick (Author) , Debus, Jürgen (Author) , Haberkorn, Uwe (Author) , Adeberg, Sebastian (Author)
Format: Article (Journal)
Language:English
Published: 19 February 2021
In: EJNMMI Research
Year: 2021, Volume: 11, Pages: 1-12
ISSN:2191-219X
DOI:10.1186/s13550-021-00761-2
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13550-021-00761-2
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Author Notes:Paul Windisch, Daniel R. Zwahlen, Frederik L. Giesel, Eberhard Scholz, Patrick Lugenbiel, Jürgen Debus, Uwe Haberkorn and Sebastian Adeberg
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Summary:Small molecules targeting fibroblast activation protein (FAP) have emerged as a new group of tracers for positron emission tomography (PET) in 2018. While most of the existing literature has been focussed on the application of FAP-specific PET in various kinds of cancers, some researchers have, both intentionally or unintentionally, used FAP-specific PET in patients with non-cancerous diseases. The purpose of this systematic review is therefore to summarize the available evidence of FAP-specific PET for non-malignant indications.
Item Description:Gesehen am 07.04.2021
Physical Description:Online Resource
ISSN:2191-219X
DOI:10.1186/s13550-021-00761-2

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