A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy

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Main Authors: Wass, Maxi (Author) , Göllner, Stefanie (Author) , Besenbeck, Birgit (Author) , Schlenk, Richard Friedrich (Author) , Mundmann, Petra (Author) , Göthert, Joachim Rudolf (Author) , Noppeney, Richard (Author) , Schliemann, Christoph (Author) , Mikesch, Jan-Henrik (Author) , Lenz, Georg (Author) , Dugas, Martin (Author) , Wermke, Martin (Author) , Röllig, Christoph (Author) , Bornhäuser, Martin (Author) , Serve, Hubert (Author) , Platzbecker, Uwe (Author) , Foerster, Kathrin (Author) , Burhenne, Jürgen (Author) , Haefeli, Walter E. (Author) , Müller, Lutz P. (Author) , Binder, Mascha (Author) , Pabst, Caroline (Author) , Müller-Tidow, Carsten (Author)
Format: Article (Journal)
Language:English
Published: 2021
In: Leukemia
Year: 2021, Volume: 35, Issue: 3, Pages: 701-711
ISSN:1476-5551
DOI:10.1038/s41375-020-0892-z
Online Access:Resolving-System, lizenzpflichtig: https://dx.doi.org/10.1038/s41375-020-0892-z
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Author Notes:Maxi Wass, Stefanie Göllner, Birgit Besenbeck, Richard F. Schlenk, Petra Mundmann, Joachim R. Göthert, Richard Noppeney, Christoph Schliemann, Jan-Henrik Mikesch, Georg Lenz, Martin Dugas, Martin Wermke, Christoph Röllig, Martin Bornhäuser, Hubert Serve, Uwe Platzbecker, Kathrin I. Foerster, Jürgen Burhenne, Walter E. Haefeli, Lutz P. Müller, Mascha Binder, Caroline Pabst, Carsten Müller-Tidow, on behalf of the Study Alliance Leukemia (SAL)
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Item Description:Online veröffentlicht: 19 June 2020
Physical Description:Online Resource
ISSN:1476-5551
DOI:10.1038/s41375-020-0892-z