The great repression: chromatin and cryptic transcription
The eukaryotic chromatin structure is essential in correctly defining transcription units. Impairing this structure can activate cryptic promoters, and lead to the accumulation of aberrant RNA transcripts. Here we discuss critical pathways that are responsible for the repression of cryptic transcrip...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
01 May 2013
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| In: |
Transcription
Year: 2013, Volume: 4, Issue: 3, Pages: 97-101 |
| ISSN: | 2154-1272 |
| DOI: | 10.4161/trns.24884 |
| Online Access: | Verlag: https://doi.org/10.4161/trns.24884
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| Author Notes: | Bianca P. Hennig & Tamás Fischer |
| Summary: | The eukaryotic chromatin structure is essential in correctly defining transcription units. Impairing this structure can activate cryptic promoters, and lead to the accumulation of aberrant RNA transcripts. Here we discuss critical pathways that are responsible for the repression of cryptic transcription and the maintenance of genome integrity. |
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| Item Description: | Gesehen am 13.04.2021 |
| Physical Description: | Online Resource |
| ISSN: | 2154-1272 |
| DOI: | 10.4161/trns.24884 |