The great repression: chromatin and cryptic transcription

The eukaryotic chromatin structure is essential in correctly defining transcription units. Impairing this structure can activate cryptic promoters, and lead to the accumulation of aberrant RNA transcripts. Here we discuss critical pathways that are responsible for the repression of cryptic transcrip...

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Hauptverfasser: Hennig, Bianca P. (VerfasserIn) , Fischer, Tamás (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 01 May 2013
In: Transcription
Year: 2013, Jahrgang: 4, Heft: 3, Pages: 97-101
ISSN:2154-1272
DOI:10.4161/trns.24884
Online-Zugang:Verlag: https://doi.org/10.4161/trns.24884
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Verfasserangaben:Bianca P. Hennig & Tamás Fischer
Beschreibung
Zusammenfassung:The eukaryotic chromatin structure is essential in correctly defining transcription units. Impairing this structure can activate cryptic promoters, and lead to the accumulation of aberrant RNA transcripts. Here we discuss critical pathways that are responsible for the repression of cryptic transcription and the maintenance of genome integrity.
Beschreibung:Gesehen am 13.04.2021
Beschreibung:Online Resource
ISSN:2154-1272
DOI:10.4161/trns.24884