Maternal and neonatal outcome and children’s development after medically assisted reproduction with in-vitro matured oocytes: a systematic review and meta-analysis

The aim of this systematic review was to evaluate the current evidence from IVM children of an impact of in-vitro culture of immature oocytes. Primary outcome parameters were birthweight and children’s development up to the age of 2 years. We also compared pregnancy pathologies and the outcome of IV...

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Bibliographic Details
Main Authors: Strowitzki, Thomas (Author) , Bruckner, Thomas (Author) , Rösner, Sabine (Author)
Format: Article (Journal)
Language:English
Published: 2021
In: Human reproduction update
Year: 2021, Volume: 27, Issue: 3, Pages: 460-473
ISSN:1460-2369
DOI:10.1093/humupd/dmaa056
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/humupd/dmaa056
Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/humupd/advance-article/doi/10.1093/humupd/dmaa056/6055418
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Author Notes:Thomas Strowitzki, Thomas Bruckner, and Sabine Roesner
Description
Summary:The aim of this systematic review was to evaluate the current evidence from IVM children of an impact of in-vitro culture of immature oocytes. Primary outcome parameters were birthweight and children’s development up to the age of 2 years. We also compared pregnancy pathologies and the outcome of IVM children and COS children in relation to maternal indications, in particular PCOS, and to the type of IVM protocols with or without ovulation trigger as the secondary outcome parameters.
Item Description:Published: 30 December 2020
Gesehen am 20.04.2021
Physical Description:Online Resource
ISSN:1460-2369
DOI:10.1093/humupd/dmaa056