Metal-free domino oligocyclization reactions of enynals and enynones with molecular oxygen
A novel metal-free direct addition of molecular oxygen to the C-C triple bond toward benzannulated oxygen-bridged seven-membered ring systems and aza[3.1.0]bicycle skeletons under 3O2 atmosphere has been described. The reaction proceeds through at least three intramolecular C-O and C-C bond forming...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
February 4, 2021
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| In: |
Organic letters
Year: 2021, Volume: 23, Issue: 4, Pages: 1291-1295 |
| ISSN: | 1523-7052 |
| DOI: | 10.1021/acs.orglett.0c04272 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1021/acs.orglett.0c04272
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| Author Notes: | Alireza Abbasi Kejani, Hormoz Khosravi, Frank Rominger, Saeed Balalaie, and Bernhard Breit |
| Summary: | A novel metal-free direct addition of molecular oxygen to the C-C triple bond toward benzannulated oxygen-bridged seven-membered ring systems and aza[3.1.0]bicycle skeletons under 3O2 atmosphere has been described. The reaction proceeds through at least three intramolecular C-O and C-C bond forming steps via green, simple, and unprecedented domino radical processes with high selectivity and good yields. |
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| Item Description: | Gesehen am 27.04.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1523-7052 |
| DOI: | 10.1021/acs.orglett.0c04272 |