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The functional genome of CA1 and CA3 neurons under native conditions and in response to ischemia

The different physiological repertoire of CA3 and CA1 neurons in the hippocampus, as well as their differing behaviour after noxious stimuli are ultimately based upon differences in the expressed genome. We have compared CA3 and CA1 gene expression in the uninjured brain, and after cerebral ischemia...

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Main Authors: Newrzella, Dieter (Author) , Pahlavan, Payam S. (Author) , Krüger, Carola (Author) , Boehm, Christine (Author) , Sorgenfrei, Oliver (Author) , Schröck, Helmut (Author) , Eisenhardt, Gisela (Author) , Bischoff, Nadine (Author) , Vogt, Gerhard (Author) , Wafzig, Oliver (Author) , Rossner, Moritz (Author) , Maurer, Martin H. (Author) , Hiemisch, Holger (Author) , Bach, Alfred (Author) , Kuschinsky, Wolfgang (Author) , Schneider, Armin (Author)
Format: Article (Journal)
Language:English
Published: 15 October 2007
In: BMC genomics
Year: 2007, Volume: 8, Pages: 1-18
ISSN:1471-2164
DOI:10.1186/1471-2164-8-370
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2164-8-370
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Author Notes:Dieter Newrzella, Payam S. Pahlavan, Carola Krüger, Christine Boehm, Oliver Sorgenfrei, Helmut Schröck, Gisela Eisenhardt, Nadine Bischoff, Gerhard Vogt, Oliver Wafzig, Moritz Rossner, Martin H. Maurer, Holger Hiemisch, Alfred Bach, Wolfgang Kuschinsky, Armin Schneider
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Summary:The different physiological repertoire of CA3 and CA1 neurons in the hippocampus, as well as their differing behaviour after noxious stimuli are ultimately based upon differences in the expressed genome. We have compared CA3 and CA1 gene expression in the uninjured brain, and after cerebral ischemia using laser microdissection (LMD), RNA amplification, and array hybridization.
Item Description:Gesehen am 30.04.2021
Physical Description:Online Resource
ISSN:1471-2164
DOI:10.1186/1471-2164-8-370

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