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Pharmacokinetic interaction of chloroquine and methylene blue combination against malaria

The combination of chloroquine and methylene blue is potentially effective for the treatment of chloroquine-resistant malaria caused by Plasmodium falciparum. The aim of this study was to investigate whether methylene blue influences the pharmacokinetics of chloroquine.

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Bibliographic Details
Main Authors: Rengelshausen, Jens (Author) , Burhenne, Jürgen (Author) , Fröhlich, Margit (Author) , Tayrouz Haffar, Yorki Antoine (Author) , Singh, Shio Kumar (Author) , Riedel, Klaus-Dieter (Author) , Müller, Olaf (Author) , Hoppe-Tichy, Torsten (Author) , Haefeli, Walter E. (Author) , Mikus, Gerd (Author) , Walter-Sack, Ingeborg (Author)
Format: Article (Journal)
Language:English
Published: 13 October 2004
In: European journal of clinical pharmacology
Year: 2004, Volume: 60, Issue: 10, Pages: 709-715
ISSN:1432-1041
DOI:10.1007/s00228-004-0818-0
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00228-004-0818-0
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Author Notes:Jens Rengelshausen, Jürgen Burhenne, Margit Fröhlich, Yorki Tayrouz, Shio Kumar Singh, Klaus-Dieter Riedel, Olaf Müller, Torsten Hoppe-Tichy, Walter E. Haefeli, Gerd Mikus, Ingeborg Walter-Sack
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Summary:The combination of chloroquine and methylene blue is potentially effective for the treatment of chloroquine-resistant malaria caused by Plasmodium falciparum. The aim of this study was to investigate whether methylene blue influences the pharmacokinetics of chloroquine.
Item Description:Gesehen am 18.05.2021
Physical Description:Online Resource
ISSN:1432-1041
DOI:10.1007/s00228-004-0818-0

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