Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

Tom Karlsen and colleagues report an association study for primary sclerosing cholangitis (PSC), a severe liver disease, using the Immunochip array. They identify nine loci newly associated with PSC and examine pleiotropy with other autoimmune disorders.

Bibliographic Details

Main Authors:	Liu, Jimmy Z. (Author) , Gotthardt, Daniel (Author)
Format:	Article (Journal)
Language:	English
Published:	21 April 2013
In:	Nature genetics Year: 2013, Volume: 45, Issue: 6, Pages: 670-675
ISSN:	1546-1718
DOI:	10.1038/ng.2616
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/ng.2616 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/ng.2616
Author Notes:	Jimmy Z. Liu, Johannes Roksund Hov, Trine Folseraas, Eva Ellinghaus, Simon M. Rushbrook, Nadezhda T. Doncheva, Ole A. Andreassen, Rinse K. Weersma, Tobias J. Weismüller, Bertus Eksteen, Pietro Invernizzi, Gideon M. Hirschfield, Daniel Nils Gotthardt, Albert Pares, David Ellinghaus, Tejas Shah, Brian D. Juran, Piotr Milkiewicz, Christian Rust, Christoph Schramm, Tobias Müller, Brijesh Srivastava, Georgios Dalekos, Markus M. Nöthen, Stefan Herms, Juliane Winkelmann, Mitja Mitrovic, Felix Braun, Cyriel Y. Ponsioen, Peter J. P. Croucher, Martina Sterneck, Andreas Teufel, Andrew L. Mason, Janna Saarela, Virpi Leppa, Ruslan Dorfman, Domenico Alvaro, Annarosa Floreani, Suna Onengut-Gumuscu, Stephen S. Rich, Wesley K. Thompson, Andrew J. Schork, Sigrid Næss, Ingo Thomsen, Gabriele Mayr, Inke R. König, Kristian Hveem, Isabelle Cleynen, Javier Gutierrez-Achury, Isis Ricaño-Ponce, David van Heel, Einar Björnsson, Richard N. Sandford, Peter R. Durie, Espen Melum, Morten H. Vatn, Mark S. Silverberg, Richard H. Duerr, Leonid Padyukov, Stephan Brand, Miquel Sans, Vito Annese, Jean-Paul Achkar, Kirsten Muri Boberg, Hanns-Ulrich Marschall, Olivier Chazouillères, Christopher L. Bowlus, Cisca Wijmenga, Erik Schrumpf, Severine Vermeire, Mario Albrecht, John D. Rioux, Graeme Alexander, Annika Bergquist, Judy Cho, Stefan Schreiber, Michael P. Manns, Martti Färkkilä, Anders M. Dale, Roger W. Chapman, Konstantinos N. Lazaridis, Andre Franke, Carl A. Anderson & Tom H. Karlsen