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Voriconazole-induced QT interval prolongation and ventricular tachycardia: a non-concentration-dependent adverse effect

A 15-year-old patient with acute lymphoblastic leukemia and Fusarium infection was treated with voriconazole. She developed asymptomatic bradycardia, QT interval prolongation, and nonsustained, polymorphic ventricular tachycardia, which recurred upon rechallenge with the drug. Voriconazole levels an...

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Main Authors: Alkan, Yoav (Author) , Haefeli, Walter E. (Author) , Burhenne, Jürgen (Author) , Stein, J. (Author) , Yaniv, I. (Author) , Shalit, Itamar (Author)
Format: Article (Journal)
Language:English
Published: 15 September 2004
In: Clinical infectious diseases
Year: 2004, Volume: 39, Issue: 6, Pages: e49-e52
ISSN:1537-6591
DOI:10.1086/423275
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1086/423275
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Author Notes:Y. Alkan, W.E. Haefeli, J. Burhenne, J. Stein, I. Yaniv, and I. Shalit

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