Xanthine oxidase inhibition by allopurinol affects the reliability of urinary caffeine metabolic ratios as markers for N-acetyltransferase 2 and CYP1A2 activities
Objectives: To evaluate the in vivo effect of xanthine oxidase (XO) inhibition by allopurinol on the determination of polymorphic N-acetyltransferase 2 (NAT2) and cytochrome P450 1A2 (CYP1A2) with urinary caffeine metabolic ratios.
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
January 1999
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| In: |
European journal of clinical pharmacology
Year: 1999, Jahrgang: 54, Heft: 11, Pages: 869-876 |
| ISSN: | 1432-1041 |
| DOI: | 10.1007/s002280050569 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s002280050569
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| Verfasserangaben: | P. Fuchs, W. E. Haefeli, H. R. Ledermann, M. Wenk |
| Zusammenfassung: | Objectives: To evaluate the in vivo effect of xanthine oxidase (XO) inhibition by allopurinol on the determination of polymorphic N-acetyltransferase 2 (NAT2) and cytochrome P450 1A2 (CYP1A2) with urinary caffeine metabolic ratios. |
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| Beschreibung: | Gesehen am 27.05.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 1432-1041 |
| DOI: | 10.1007/s002280050569 |