Surgical treatment of pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) represents an aggressive tumor of the digestive system with still low five-year survival of less than 10%. Although there are improvements for multimodal therapy of PDAC, surgery still remains the effective way to treat the disease. Combined with adjuvant and/...

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Bibliographic Details
Main Authors: Wei, Kongyuan (Author) , Hackert, Thilo (Author)
Format: Article (Journal)
Language:English
Published: 20 April 2021
In: Cancers
Year: 2021, Volume: 13, Issue: 8, Pages: 1-16
ISSN:2072-6694
DOI:10.3390/cancers13081971
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/cancers13081971
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2072-6694/13/8/1971
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Author Notes:Kongyuan Wei and Thilo Hackert
Description
Summary:Pancreatic ductal adenocarcinoma (PDAC) represents an aggressive tumor of the digestive system with still low five-year survival of less than 10%. Although there are improvements for multimodal therapy of PDAC, surgery still remains the effective way to treat the disease. Combined with adjuvant and/or neoadjuvant treatment, pancreatic surgery is able to enhance the five-year survival up to around 20%. However, pancreatic resection is always associated with a high risk of complications and regarded as one of the most complex fields in abdominal surgery. This review gives a summary on the surgical treatment for PDAC based on the current literature with a special focus on resection techniques.
Item Description:Gesehen am 01.06.2021
Physical Description:Online Resource
ISSN:2072-6694
DOI:10.3390/cancers13081971