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A2BC-type porphyrin SAM on gold surface for bacteria detection applications: synthesis and surface functionalization

Currently used elaborate technologies for the detection of bacteria can be improved in regard to their time consumption, labor intensity, accuracy and reproducibility. Well-known electrical measurement methods might connect highly sensitive sensing systems with biological requirements. The developme...

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Main Authors: Neumann, Laurie (Author) , Könemund, Lea (Author) , Rohnacher, Valentina (Author) , Pucci, Annemarie (Author) , Johannes, Hans-Hermann (Author) , Kowalsky, Wolfgang (Author)
Format: Article (Journal)
Language:English
Published: 13 April 2021
In: Materials
Year: 2021, Volume: 14, Issue: 8, Pages: 1-14
ISSN:1996-1944
DOI:10.3390/ma14081934
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/ma14081934
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/1996-1944/14/8/1934
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Author Notes:Laurie Neumann, Lea Könemund, Valentina Rohnacher, Annemarie Pucci, Hans-Hermann Johannes and Wolfgang Kowalsky
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Summary:Currently used elaborate technologies for the detection of bacteria can be improved in regard to their time consumption, labor intensity, accuracy and reproducibility. Well-known electrical measurement methods might connect highly sensitive sensing systems with biological requirements. The development of modified sensor surfaces with self-assembled monolayers (SAMs) from functionalized porphyrin for bacteria trapping can lead to a highly sensitive sensor for bacteria detection. Different A2BC-type porphyrin structures were synthesized and examined regarding their optical behavior. We achieved the synthesis of a porphyrin for SAM formation on a gold surface as electrode material. Two possible bio linkers were attached on the opposite meso-position of the porphyrin, which allows the porphyrin to react as a linker on the surface for bacteria trapping. Different porphyrin structures were attached to a gold surface, the SAM formation and the respective coverage was investigated.
Item Description:Gesehen am 02.06.2021
Im Titel ist "2" tiefgestellt
Physical Description:Online Resource
ISSN:1996-1944
DOI:10.3390/ma14081934

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