Multiple glutathione disulfide removal pathways mediate cytosolic redox homeostasis
Quantification of cytosolic glutathione redox potential leads to the discovery that the ABC-C transporter Ycf1 rapidly transports oxidized glutathione (GSSG) into vacuoles and whole-cell GSSG should not be used as a proxy for cytosolic GSSG.
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| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2013
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| In: |
Nature chemical biology
Year: 2012, Jahrgang: 9, Heft: 2, Pages: 119-125 |
| ISSN: | 1552-4469 |
| DOI: | 10.1038/nchembio.1142 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nchembio.1142 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nchembio.1142 |
| Verfasserangaben: | Bruce Morgan, Daria Ezeriņa, Theresa N.E. Amoako, Jan Riemer, Matthias Seedorf & Tobias P. Dick |
| Zusammenfassung: | Quantification of cytosolic glutathione redox potential leads to the discovery that the ABC-C transporter Ycf1 rapidly transports oxidized glutathione (GSSG) into vacuoles and whole-cell GSSG should not be used as a proxy for cytosolic GSSG. |
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| Beschreibung: | Published: 16 December 2012 Gesehen am 07.06.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 1552-4469 |
| DOI: | 10.1038/nchembio.1142 |