Localization of the Wilson's disease protein in human liver
Wilson's disease is an autosomal-recessive disorder of copper metabolism that results from the absence or dysfunction of a copper-transporting P-type adenosine triphosphatase that leads to impaired biliary copper excretion and disturbed holoceruloplasmin synthesis. To gain further insight into...
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| Main Authors: | , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
1999
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| In: |
Gastroenterology
Year: 1999, Volume: 117, Issue: 6, Pages: 1380-1385 |
| ISSN: | 1528-0012 |
| DOI: | 10.1016/S0016-5085(99)70288-X |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/S0016-5085(99)70288-X Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S001650859970288X |
| Author Notes: | Mark Schaefer, Han Roelofsen, Henk Wolters, Walter J. Hofmann, Michael Müller, Folkert Kuipers, Wolfgang Stremmel, and Roel J. Vonk |
| Summary: | Wilson's disease is an autosomal-recessive disorder of copper metabolism that results from the absence or dysfunction of a copper-transporting P-type adenosine triphosphatase that leads to impaired biliary copper excretion and disturbed holoceruloplasmin synthesis. To gain further insight into the role of the Wilson's disease protein in hepatic copper handling, its localization in human liver was investigated. |
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| Item Description: | Elektronische Reproduktion der Print-Ausgabe, 28 October 2005 Gesehen am 08.06.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1528-0012 |
| DOI: | 10.1016/S0016-5085(99)70288-X |