The effect of pramlintide (amylin analogue) treatment on bone metabolism and bone density in patients with type 1 diabetes mellitus
Amylin is a 37-amino-acid peptide related to CGRP and calcitonin. It is co-secreted with insulin from pancreatic β-cells. Amylin is deficient with type 1 diabetes mellitus. To study the in vivo effects of amylin in humans, diabetic patients are an adequate model of chronic amylin deficiency. We inve...
Guardado en:
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Article (Journal) |
| Lenguaje: | inglés |
| Publicado: |
1999
|
| In: |
Hormone and metabolic research
Year: 1999, Volumen: 31, Número: 8, Pages: 472-475 |
| ISSN: | 1439-4286 |
| DOI: | 10.1055/s-2007-978777 |
| Acceso en línea: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1055/s-2007-978777 Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-2007-978777 
|
| Notas de Autor: | A.K. Borm, M.S. Klevesath, V. Borcea, C. Kasperk, M.J. Seibel, P. Wahl, R. Ziegler, P.P. Nawroth |
| Sumario: | Amylin is a 37-amino-acid peptide related to CGRP and calcitonin. It is co-secreted with insulin from pancreatic β-cells. Amylin is deficient with type 1 diabetes mellitus. To study the in vivo effects of amylin in humans, diabetic patients are an adequate model of chronic amylin deficiency. We investigated the effect of a 12 months pramlintide therapy (amylin analogue) on bone metabolism in patients with type 1 diabetes mellitus. |
|---|---|
| Notas: | Elektronische Reproduktion der Druck-Ausgabe, 20. April 2007 Gesehen am 09.06.2021 |
| Descripción Física: | Online Resource |
| ISSN: | 1439-4286 |
| DOI: | 10.1055/s-2007-978777 |