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Proposal for a unified norovirus nomenclature and genotyping

Noroviruses belong to a genus of genetically diverse viruses within the family Caliciviridae and cause acute gastroenteritis in humans and animals. They are subdivided into genogroups, each of which further segregates into genotypes. Until recently, a new genotype was based on a defined pairwise dis...

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Main Authors: Kroneman, Annelies (Author) , Vega, Everardo (Author) , Vennema, Harry (Author) , Vinjé, Jan (Author) , White, Peter A. (Author) , Hansman, Grant S. (Author) , Green, Kim (Author) , Martella, Vito (Author) , Katayama, Kazuhiko (Author) , Koopmans, Marion (Author)
Format: Article (Journal)
Language:English
Published: 25 April 2013
In: Archives of virology
Year: 2013, Volume: 158, Issue: 10, Pages: 2059-2068
ISSN:1432-8798
DOI:10.1007/s00705-013-1708-5
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00705-013-1708-5
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Author Notes:Annelies Kroneman, Everardo Vega, Harry Vennema, Jan Vinjé, Peter A. White, Grant Hansman, Kim Green, Vito Martella, Kazuhiko Katayama, Marion Koopmans
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Summary:Noroviruses belong to a genus of genetically diverse viruses within the family Caliciviridae and cause acute gastroenteritis in humans and animals. They are subdivided into genogroups, each of which further segregates into genotypes. Until recently, a new genotype was based on a defined pairwise distance cutoff of complete VP1 sequences, but with the increasing number of available norovirus sequences, this cutoff is no longer accurate, and sequences in the public database have been misclassified. In this paper, we demonstrate that the pairwise distance cutoff method can no longer be used and outline a phylogenetic approach to classify noroviruses. Furthermore, we propose a dual nomenclature using both ORF1 and VP1 sequences, as recombination is common and recognizing recombinant viruses may be relevant. With the continuing emergence of new norovirus lineages, we propose to coordinate nomenclature of new norovirus genotypes through an international norovirus working group.
Item Description:Gesehen am 14.06.2021
Physical Description:Online Resource
ISSN:1432-8798
DOI:10.1007/s00705-013-1708-5

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