Novel serum markers of bone resorption: clinical assessment and comparison with established urinary indices
Although urinary measurements of collagen degradation provide valid estimates of bone resorption, their clinical application is hampered by pronounced analytical and biological variability. Therefore, immunoassays for the determination of such parameters in serum have been developed. In this study,...
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| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
1999
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| In: |
Journal of bone and mineral research
Year: 1999, Jahrgang: 14, Heft: 5, Pages: 792-801 |
| ISSN: | 1523-4681 |
| DOI: | 10.1359/jbmr.1999.14.5.792 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1359/jbmr.1999.14.5.792 Verlag, lizenzpflichtig, Volltext: https://asbmr.onlinelibrary.wiley.com/doi/abs/10.1359/jbmr.1999.14.5.792 
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| Verfasserangaben: | Henning W. Woitge, Martin Pecherstorfer, Yuming Li, Andrea-V. Keck, Eva Horn, Reinhard Ziegler, and Markus J. Seibel |
| Zusammenfassung: | Although urinary measurements of collagen degradation provide valid estimates of bone resorption, their clinical application is hampered by pronounced analytical and biological variability. Therefore, immunoassays for the determination of such parameters in serum have been developed. In this study, we assessed the performance of three new serum markers of bone turnover, i.e., C-terminal and N-terminal telopeptides of type I collagen (S-CTX and S-NTX) and bone sialoprotein. |
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| Beschreibung: | Elektronische Reproduktion der Druck-Ausgabe, 02 December 2009 Gesehen am 15.06.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 1523-4681 |
| DOI: | 10.1359/jbmr.1999.14.5.792 |