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Octreotide (somatostatin analog) treatment reduces endothelial cell dysfunction in patients with diabetes mellitus

Octreotide is a long-acting somatostatin analog that has been shown to have various effects in diabetes. This study was performed to evaluate whether octreotide affects the vascular complications of diabetes mellitus. Albuminuria and serum thrombomodulin were used as markers of vascular and renal dy...

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Main Authors: Clemens, Andreas (Author) , Klevesath, Martina (Author) , Hofmann Bowman, Marion (Author) , Raulf, Friedrich (Author) , Henkels, Mechthild (Author) , Amiral, Jean (Author) , Seibel, Markus J. (Author) , Zimmermann, Jürgen (Author) , Ziegler, Reinhard (Author) , Wahl, Peter (Author) , Nawroth, Peter Paul (Author)
Format: Article (Journal)
Language:English
Published: October 1999
In: Metabolism
Year: 1999, Volume: 48, Issue: 10, Pages: 1236-1240
ISSN:1532-8600
DOI:10.1016/S0026-0495(99)90261-5
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/S0026-0495(99)90261-5
Verlag, lizenzpflichtig, Volltext: https://www.metabolismjournal.com/article/S0026-0495(99)90261-5/abstract
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Author Notes:Andreas Clemens, Martina S. Klevesath, Marion Hofmann, Friedrich Raulf, Mechthild Henkels, Jean Amiral, Markus J. Seibel, Jürgen Zimmermann, Reinhard Ziegler, Peter Wahl, and Peter P. Nawroth
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Summary:Octreotide is a long-acting somatostatin analog that has been shown to have various effects in diabetes. This study was performed to evaluate whether octreotide affects the vascular complications of diabetes mellitus. Albuminuria and serum thrombomodulin were used as markers of vascular and renal dysfunction. We studied the effect of octreotide in 27 patients with insulin-dependent diabetes mellitus (IDDM).
Item Description:Gesehen am 18.06.2021
Physical Description:Online Resource
ISSN:1532-8600
DOI:10.1016/S0026-0495(99)90261-5

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