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Effectiveness and cost-effectiveness of four different strategies for SARS-CoV-2 surveillance in the general population (CoV-Surv Study): a structured summary of a study protocol for a cluster-randomised, two-factorial controlled trial

In this cluster-randomised controlled study (CoV-Surv Study), four different “active” SARS-CoV-2 testing strategies for general population surveillance are evaluated for their effectiveness in determining and predicting the prevalence of SARS-CoV-2 infections in a given population. In addition, the...

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Main Authors: Deckert, Andreas (Author) , Anders, Simon (Author) , De Allegri, Manuela (Author) , Nguyen, Hoa Thi (Author) , Souares-Coutant, Aurélia (Author) , McMahon-Rössle, Shannon A. (Author) , Börner, Kathleen (Author) , Meurer, Matthias (Author) , Herbst, Konrad (Author) , Sand, Matthias (Author) , Köppel, Lisa (Author) , Siems, Tobias (Author) , Brugnara Kirchmann, Lúcia (Author) , Brenner, Stephan (Author) , Burk, Robin (Author) , Lou, Dan (Author) , Kirrmaier, Daniel (Author) , Duan, Yuanqiang (Author) , Ovchinnikova, Svetlana (Author) , Marx, Michael (Author) , Kräusslich, Hans-Georg (Author) , Knop, Michael (Author) , Bärnighausen, Till (Author) , Denkinger, Claudia M. (Author)
Format: Article (Journal)
Language:English
Published: 08 January 2021
In: Trials
Year: 2021, Volume: 22, Pages: 1-4
ISSN:1468-6694
DOI:10.1186/s13063-020-04982-z
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13063-020-04982-z
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Author Notes:Andreas Deckert, Simon Anders, Manuela de Allegri, Hoa Thi Nguyen, Aurélia Souares, Shannon McMahon, Kathleen Boerner, Matthias Meurer, Konrad Herbst, Matthias Sand, Lisa Koeppel, Tobias Siems, Lucia Brugnara, Stephan Brenner, Robin Burk, Dan Lou, Daniel Kirrmaier, Yuanqiang Duan, Svetlana Ovchinnikova, Michael Marx, Hans Georg Kräusslich, Michael Knop, Till Bärnighausen and Claudia Denkinger
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Summary:In this cluster-randomised controlled study (CoV-Surv Study), four different “active” SARS-CoV-2 testing strategies for general population surveillance are evaluated for their effectiveness in determining and predicting the prevalence of SARS-CoV-2 infections in a given population. In addition, the costs and cost-effectiveness of the four surveillance strategies will be assessed. Further, this trial is supplemented by a qualitative component to determine the acceptability of each strategy. Findings will inform the choice of the most effective, acceptable and affordable strategy for SARS-CoV-2 surveillance, with the most effective and cost-effective strategy becoming part of the local public health department’s current routine health surveillance activities. Investigating its everyday performance will allow us to examine the strategy’s applicability to real time prevalence prediction and the usefulness of the resulting information for local policy makers to implement countermeasures that effectively prevent future nationwide lockdowns.
Item Description:Gesehen am 22.06.2021
Physical Description:Online Resource
ISSN:1468-6694
DOI:10.1186/s13063-020-04982-z

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