Emotion dysregulation in borderline personality disorder: a fronto-limbic imbalance?

Borderline personality disorder is most consistently characterized as a disorder of the experience and regulation of emotions. Neuropathological models have predominantly explained these clinical traits with an imbalance between prefrontal regulatory and limbic emotion generating structures. Here, w...

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Bibliographic Details
Main Authors: Sicorello, Maurizio (Author) , Schmahl, Christian (Author)
Format: Article (Journal)
Language:English
Published: February 2021
In: Current opinion in psychology
Year: 2021, Volume: 37, Pages: 114-120
ISSN:2352-250X
DOI:10.1016/j.copsyc.2020.12.002
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.copsyc.2020.12.002
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S2352250X20302128
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Author Notes:Maurizio Sicorello and Christian Schmahl
Description
Summary:Borderline personality disorder is most consistently characterized as a disorder of the experience and regulation of emotions. Neuropathological models have predominantly explained these clinical traits with an imbalance between prefrontal regulatory and limbic emotion generating structures. Here, we review the current evidential state of the fronto-limbic imbalance hypothesis of borderline personality disorder, based on task-related functional magnetic resonance imaging research. In turn, we discuss challenges to the notion that (1) amygdala hyperreactivity underlies emotional hyperreactivity and deficits in (2) prefrontal activity or (3) fronto-limbic connectivity underly emotion regulation deficits. We offer several suggestions to improve consolidation and interpretation of research in this area.
Item Description:Gesehen am 05.07.2021
Physical Description:Online Resource
ISSN:2352-250X
DOI:10.1016/j.copsyc.2020.12.002