Emotion dysregulation in borderline personality disorder: a fronto-limbic imbalance?

Borderline personality disorder is most consistently characterized as a disorder of the experience and regulation of emotions. Neuropathological models have predominantly explained these clinical traits with an imbalance between prefrontal regulatory and limbic emotion generating structures. Here, w...

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Hauptverfasser: Sicorello, Maurizio (VerfasserIn) , Schmahl, Christian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: February 2021
In: Current opinion in psychology
Year: 2021, Jahrgang: 37, Pages: 114-120
ISSN:2352-250X
DOI:10.1016/j.copsyc.2020.12.002
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.copsyc.2020.12.002
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S2352250X20302128
Volltext
Verfasserangaben:Maurizio Sicorello and Christian Schmahl
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Zusammenfassung:Borderline personality disorder is most consistently characterized as a disorder of the experience and regulation of emotions. Neuropathological models have predominantly explained these clinical traits with an imbalance between prefrontal regulatory and limbic emotion generating structures. Here, we review the current evidential state of the fronto-limbic imbalance hypothesis of borderline personality disorder, based on task-related functional magnetic resonance imaging research. In turn, we discuss challenges to the notion that (1) amygdala hyperreactivity underlies emotional hyperreactivity and deficits in (2) prefrontal activity or (3) fronto-limbic connectivity underly emotion regulation deficits. We offer several suggestions to improve consolidation and interpretation of research in this area.
Beschreibung:Gesehen am 05.07.2021
Beschreibung:Online Resource
ISSN:2352-250X
DOI:10.1016/j.copsyc.2020.12.002