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Pediatric case report on magnetic resonance imaging/transrectal ultrasound-fusion biopsy of rhabdomyosarcoma of the bladder/prostate: a new tool to reduce therapy-associated morbidity?

Rhabdomyosarcomas are the most common soft tissue sarcomas in children. Here we present management of an 18-month-old boy with metastatic rhabdomyosarcoma of the bladder/prostate. After radiochemotherapy, high-spatial-resolution 3-Tesla multiparametric magnetic resonance imaging (MRI) showed regress...

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Main Authors: Kuru, Timur Hasan (Author) , Röthke, Matthias C. (Author) , Nyarangi-Dix, Joanne (Author) , Okouoyo, Stella (Author) , Stockklausner, Clemens (Author) , Schenk, Jens-Peter (Author) , Debus, Jürgen (Author) , Roth, Wilfried (Author) , Teber, Dogu (Author) , Pahernik, Sascha (Author) , Schlemmer, Heinz-Peter (Author) , Hohenfellner, Markus (Author) , Hadaschik, Boris (Author)
Format: Article (Journal)
Language:English
Published: 30 January 2013
In: Urology
Year: 2013, Volume: 81, Issue: 2, Pages: 417-420
ISSN:1527-9995
DOI:10.1016/j.urology.2012.10.043
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.urology.2012.10.043
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0090429512013416
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Author Notes:Timur H. Kuru, Matthias C. Roethke, Joanne Nyarangi-Dix, Stella Okouoyo, Clemens Stockklausner, Jens-Peter Schenk, Jürgen Debus, Wilfried Roth, Dogu Teber, Sascha Pahernik, Heinz-Peter Schlemmer, Markus Hohenfellner, and Boris A. Hadaschik
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Summary:Rhabdomyosarcomas are the most common soft tissue sarcomas in children. Here we present management of an 18-month-old boy with metastatic rhabdomyosarcoma of the bladder/prostate. After radiochemotherapy, high-spatial-resolution 3-Tesla multiparametric magnetic resonance imaging (MRI) showed regressive systemic disease but a residual mass at the right seminal vesicle. For histologic re-evaluation, 3-dimensional-controlled stereotactic MRI/transrectal ultrasound (TRUS)-fusion biopsy specimens were taken. Because histologic analysis showed nonvital tissue, a decision could be made against adjuvant radical cystoprostatectomy. Advanced 3-Tesla imaging and MRI/TRUS-fusion biopsies in children are feasible and represent an effective tool to examine suspicious pelvic lesions. Depending on histology, this can lead to a significant reduction of therapy-associated morbidity.
Item Description:Gesehen am 12.07.2021
Physical Description:Online Resource
ISSN:1527-9995
DOI:10.1016/j.urology.2012.10.043

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