Plasmodium vinckei genomes provide insights into the pan-genome and evolution of rodent malaria parasites

Rodent malaria parasites (RMPs) serve as tractable tools to study malaria parasite biology and host-parasite-vector interactions. Among the four RMPs originally collected from wild thicket rats in sub-Saharan Central Africa and adapted to laboratory mice, Plasmodium vinckei is the most geographicall...

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Main Authors: Ramaprasad, Abhinay (Author) , Klaus, Severina (Author) , Douvropoulou, Olga (Author) , Culleton, Richard (Author) , Pain, Arnab (Author)
Format: Article (Journal)
Language:English
Published: Apr 23 2021
In: BMC biology
Year: 2021, Volume: 19, Pages: 1-22
ISSN:1741-7007
DOI:10.1186/s12915-021-00995-5
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12915-021-00995-5
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Author Notes:Abhinay Ramaprasad, Severina Klaus, Olga Douvropoulou, Richard Culleton and Arnab Pain
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Summary:Rodent malaria parasites (RMPs) serve as tractable tools to study malaria parasite biology and host-parasite-vector interactions. Among the four RMPs originally collected from wild thicket rats in sub-Saharan Central Africa and adapted to laboratory mice, Plasmodium vinckei is the most geographically widespread with isolates collected from five separate locations. However, there is a lack of extensive phenotype and genotype data associated with this species, thus hindering its use in experimental studies.
Item Description:Gesehen am 23.07.2021
Physical Description:Online Resource
ISSN:1741-7007
DOI:10.1186/s12915-021-00995-5