Plasmodium vinckei genomes provide insights into the pan-genome and evolution of rodent malaria parasites
Rodent malaria parasites (RMPs) serve as tractable tools to study malaria parasite biology and host-parasite-vector interactions. Among the four RMPs originally collected from wild thicket rats in sub-Saharan Central Africa and adapted to laboratory mice, Plasmodium vinckei is the most geographicall...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
Apr 23 2021
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| In: |
BMC biology
Year: 2021, Volume: 19, Pages: 1-22 |
| ISSN: | 1741-7007 |
| DOI: | 10.1186/s12915-021-00995-5 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12915-021-00995-5
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| Author Notes: | Abhinay Ramaprasad, Severina Klaus, Olga Douvropoulou, Richard Culleton and Arnab Pain |
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| 520 | |a Rodent malaria parasites (RMPs) serve as tractable tools to study malaria parasite biology and host-parasite-vector interactions. Among the four RMPs originally collected from wild thicket rats in sub-Saharan Central Africa and adapted to laboratory mice, Plasmodium vinckei is the most geographically widespread with isolates collected from five separate locations. However, there is a lack of extensive phenotype and genotype data associated with this species, thus hindering its use in experimental studies. | ||
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